The Vaginal-PVPA: A Vaginal Mucosa-Mimicking In Vitro Permeation Tool for Evaluation of Mucoadhesive Formulations
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چکیده
منابع مشابه
Vaginal chitosan tablets with clotrimazole-design and evaluation of mucoadhesive properties using porcine vaginal mucosa, mucin and gelatine.
Topical administration of clotrimazole represents the common use therapy in the antimycotic genitourinary tract treatment. Due to the fast self-cleaning action of the vagina, commercially available vaginal dosage forms with clotrimazole cannot assure prolonged contact time with mucosa, therefore the main objective of this study was to develop a dosage form for vaginal administration of clotrima...
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Relatively simple and rapid procedures have been developed for evaluating the local efficacy of vaginal antifungal agents in vivo in a vaginal candidiasis model in ovariectomized rats. The results of this investigation indicate that the model and methods described are quite suitable for screening potential antifungal substances and for assessing the chemotherapeutic effectiveness of new antifun...
متن کاملFormulation and Evaluation of Mucoadhesive Vaginal Films of Ketoconazole
Address for correspondence Mr. Arshad Bashir Khan, Associate Professor, Department of Pharmaceutics, Krupanidhi College of Pharmacy, #12/1, Chikkabellandur, Carmelaram Post, Bangalore560035, India. Phone No: +91 9740379897 E-mail: [email protected] ABSTRACT Purpose: The aim of the present study was to formulate and evaluate mucoadhesive films containing Ketoconazole (KT) for the treatment of vag...
متن کاملDesign, development and in vitro evaluation of sertaconazole mucoadhesive vaginal tablet
In present study, mucoadhesive vaginal tablet of sertaconazole was designed using a combination of mucoadhesive polymers like Carbopol 934P, chitosan, carboxymethylcellulose sodium, sodium alginate, methyl cellulose, hydroxypropyl methylcellulose and hydroxypropyl cellulose. Effervescent was incorporated into formulations to enhance swellabilty of mucoadhesive tablet. For various drug-free form...
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Kunovac Kallak, T. 2015. Hormonal Regulation of Vaginal Mucosa. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1076. 65 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9181-9. Vaginal atrophy symptoms such as dryness, irritation, and itching, are common after menopause. Vaginal estrogen therapy is the most effective treatment but not appropria...
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ژورنال
عنوان ژورنال: Pharmaceutics
سال: 2020
ISSN: 1999-4923
DOI: 10.3390/pharmaceutics12060568